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Background and Aims:  1 Spinal anesthesia is widely useda accepted technique in in elective cesarean sections. However, hypotension resulted from sympathectomy is a commonly results in hypotension problem, especially particularly in pregnant women. The prophylactic use of Prevention of this complication by sympathomimetic agents may help prevent this complicationis of potential clinical significance. The aim of this study is This study aimed to compare the effect of the prophylactic infusion of Pphenylephrine versus Eephedrine toin the prevention of hypotension during spinal anesthesia in elective cesarean sections.

Methods: Eighty-three pregnant womenpatients 2 were enrolled in this study and randomly divided into three groups.: Group the Ph group received phenylephrine infusion, group the E group received ephedrine infusion, and while group the P group received were delivered a placebo. Vital signs (blood pressure, heart rate, and arterial oxygen saturation) were recorded throughout the surgery. The incidence of Mmaternal and neonatal perioperative complications waswere also comparedalso controlled and recorded among the groups.

Results: Demographic characteristics were comparable There was an insignificant difference in among demographic data between the three groups. Systolic and diastolic blood pressures were higher in the phenylephrine Ph group was higher than that in controlthe P group, but not higher than that in the the ephedrine E group. Maternal dysrhythmias were more common in the Eephedrine and Phphenylephrine groups than in the P control group. Vomiting was significantly more common in the ephedrine group E group (P < 0.05). 3 In addition, the mean fifth5-minute Apgar score of neonates was higher in the Phphenylephrine and E ephedrine groups was significantly higher than that in the P control group (P < 0.05). The incidence of neonatal acidosis in Neonates of phenylephrine the Ph group was lower than that in had less acidosis than the other two groups.

Conclusion: Prophylactic infusion of phenylephrine can effectively alleviatedecrease spinal anesthesia- related hypotension without causing any majorsignificant maternal or fetal complications for mother or her fetal.

Explanations

Spinal anesthesia is widely useda accepted technique in in elective cesarean sections. However, hypotension resulted resulting from sympathectomy is a common problemissue, especially particularly in pregnant women. The pPrevention of this complication by using sympathomimetic agents is of potential clinical significance. The aim of this study is was to compare the effect of the prophylactic infusion of Pphenylephrine versus Eephedrine toin the prevention of hypotension during spinal anesthesia in in elective cesarean sections.

Methods: Eighty-three pregnant womenpatients 1 were enrolled in this study and randomly divided into three groups.: Group the Ph group received phenylephrine infusion, group the E group received ephedrine infusion, and while group the P group received were delivered a placebo. Vital signs (blood pressure, heart rate, and arterial oxygen saturation) were recorded throughout the surgery. The incidence of Mmaternal and neonatal perioperative complications waswere also controlled and recorded.

Results: There was no an insignificant difference in demographic data between among the groups. Systolic and diastolic blood pressures were was higher in the phenylephrine group Ph group than in controlthe P group, but not higher than that in the ephedrine groupE group. Maternal dysrhythmias were more common in the Eephedrine and Phphenylephrine groups than in the control groupP group. Vomiting was more common in ephedrine group the E group (P < 2 0.05). In addition, the fifth-minute Apgar score of neonates was higher in the Phphenylephrine and E ephedrine groups than in the control P group (P < 0.05). Neonates of in the Ph phenylephrine group had less a lower incidence of acidosis than those 3 in the other two groups.

Conclusion: Prophylactic infusion of phenylephrine maycan effectively decrease spinal anesthesia- related hypotension without causing any significant complication for in the mother or her fetalfetus.

Explanations

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