免疫学分野の英文校正サンプル

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ABSTRACT

Objective: Although perioperativePerioperative immune-enhancing enteral formula (IEEF) effectively reduces theis effective to decrease rate of infectious complications that are infective, but whether the its chronic use of IEEF isare 1 beneficial is remains unknownnot known to us. A prospective Prospective randomized clinical trial was performedundertaken. This was done in order to examine the safety and effectiveness impact of the long-term IEEF on the nutritionalnutrition condition and immunological status of nonsurgical in non surgery patients receiving under total enteral nutrition through the gastrostomy access route. A total of 30 patients was randomly asigned to two groups.

Methods: This study involved 30 patients who were randomly divided into twoTwo groups: 2 receiving recieved total enteral nutrition either with IEEF immune-enhancing enteral formula  3 (Group IEEF, n = 15) or with regular polymeric enteral formula (Group C, n = 4 1514) for 12 weeks. NutritionalNutrition and immunological parameters were periodically examined periodically.

Results: The serum levels A significant increase of serum levels of insulin-likea growth factor 1 (similar to insulin, IGF-1)I significantly increased, was noted in Group IEEF throughout the course of the study. Furthermore, theWhile serum levels level of dihomo-g-linoleic acid in Group IEEF was significantly decreased and those, serum levels of eicosapentaenoiceicosa-pentaenoic acid and docosahexaenoic acidsdochsa-hexaenoic acid were significantly increasedas well as those of. Serum arginine and ornithine concentrations in Group IEEF were significantly increased significantly increased in Group IEEF. No significant difference was noted in the CD4/CD8 ratio and NK cell activity between the two groups were observed in Group IEEF, but the difference was not significant. TheA significant increase of B-cell fraction significantly increased, while and the the decrease of T-cell fraction of peripheral lymphocytes significantly decreased were observed in Group IEEF. NoThere was no infectious orand noninfectiousnon-infectious 5 complications occurred during the study period in either groupboth groups, except for a significant increase in the serum levels of blood urea nitrogenBUN and uric acid concentration.

Conclusion: The longLong-term use of IEEF is safe safely performed in nonsurgicalnon-surgery patients and results in, which enables to cause a significant increase in the of serum levels of IGF-1I concentration associated with increasedincrease in humoral immunity.

Explanations

ABSTRACT

Objective: Perioperative immune-enhancing enteral formula (IEEF) is effective to decrease reduce the rate of infectious complications that are infective, but whether the chronic use of IEEF isare beneficial is not known to us. A pProspective randomized clinical trial was performedundertaken. This was done in order to examine the safety and effectiveness impact of the long-term IEEF on the nutritional condition and immunological status of in non surgery patients receiving under total enteral nutrition through the  1 gastrostomy access route. A total of 30 patients was were randomly assigned to two groups in the present study.

Methods: The tTwo groups recievedreceived total enteral nutrition either with IEEF immune-enhancing enteral formula  2 (Group IEEF, n = 15) or with regular polymeric enteral formula (Group C, n = 3 1514) for 12 weeks. Nutritional and immunological parameters were periodically examined.

Results: A significant increase of in the serum levels of insulin-likea growth factor 1 (similar to insulin, IGF-1)I , was noted in Group IEEF throughout the course of the study. Furthermore, theWhile serum levels of dihomo-g-linoleic acid in Group IEEF was significantly decreased and those, serum levels of eicosapentaenoiceicosa-pentaenoic acid and docosahexaenoic acidsdochsa-hexaenoic acid were significantly increased in Group IEEF. Serum The serum levels of arginine and ornithine concentrations also increased significantly in Group IEEF were significantly increased. No significant difference was noted in the CD4/CD8 ratio and NK cell activity were observed in Group IEEF, but the difference was not significant. A significant increase of in the B-cell fraction and the decrease of in the T-cell fraction of peripheral lymphocytes were observed in Group IEEF. There was no infectious orand noninfectiousnon-infectious complications occurred during the study period in both groups, except for a significant increase in the serum levels of BUN and uric acid concentration.

Conclusion: The longLong-term use of IEEF is safe safely performed in non-surgery patients and results in, which enables to cause a significant increase in the of serum levels of IGF-1I concentration associated with an increase in humoral immunity.

Explanations

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