{"id":6830,"date":"2019-01-24T13:33:46","date_gmt":"2019-01-24T04:33:46","guid":{"rendered":"https:\/\/www.enago.com\/academy\/jp\/?p=6830"},"modified":"2021-12-17T00:32:33","modified_gmt":"2021-12-16T15:32:33","slug":"ethical-problem-on-research-publishing","status":"publish","type":"post","link":"https:\/\/www.enago.com\/academy\/jp\/ethical-problem-on-research-publishing\/","title":{"rendered":"\u502b\u7406\u7684\u554f\u984c\u306e\u3042\u308b\u7814\u7a76\u8ad6\u6587\u3092\u516c\u8868\u3059\u3079\u304d\u304b\uff1f"},"content":{"rendered":"<p><a href=\"https:\/\/www.enago.jp\/academy\/genome-editing-in-china\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u672c\u8a8c<\/a>\u3067\u3082\u304a\u4f1d\u3048\u3057\u3066\u3044\u308b\u901a\u308a\u30012018\u5e7411\u6708\u672b\u3001\u4e2d\u56fd\u306e\u7814\u7a76\u8005\u304c\u3001\u30d2\u30c8\u306e\u53d7\u7cbe\u5375\u306b\u300c\u30b2\u30ce\u30e0\u7de8\u96c6\u300d\u3092\u884c\u3063\u3066\u3001\u907a\u4f1d\u5b50\u3092\u6539\u5909\u3055\u305b\u305f\u8d64\u3061\u3083\u3093\u3092\u8a95\u751f\u3055\u305b\u305f\u3068\u767a\u8868\u3057\u3001\u4e16\u754c\u3092\u9a12\u7136\u3068\u3055\u305b\u307e\u3057\u305f\u3002\u30b2\u30ce\u30e0\u7de8\u96c6\u3068\u306f\u3001\u307e\u308b\u3067\u6587\u7ae0\u3092\u30ef\u30fc\u30c9\u3067\u66f8\u304d\u63db\u3048\u308b\u3088\u3046\u306b\u3001\u907a\u4f1d\u5b50\u304c\u542b\u307e\u308c\u3066\u3044\u308bDNA\u3092\u5207\u308a\u8cbc\u308a\u3059\u308b\u6280\u8853\u306e\u3053\u3068\u3067\u3059\u3002\u3072\u3068\u6614\u524d\u306e\u300c\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u6280\u8853\u300d\u306b\u6bd4\u3079\u308b\u3068\u3001\u6b63\u78ba\u3055\u3082\u6210\u529f\u7387\u3082\u683c\u6bb5\u306b\u9ad8\u3044\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u30b2\u30ce\u30e0\u7de8\u96c6\u3092\u3001\u4eba\u9593\u306e\u300c\u4f53\u7d30\u80de\u300d\u3067\u306f\u306a\u304f\u300c\u53d7\u7cbe\u5375\u300d\u306a\u3069\u306b\u884c\u3048\u3070\u3001\u7de8\u96c6\u306e\u7d50\u679c\u306f\u751f\u307e\u308c\u3066\u304f\u308b\u5b50\u3069\u3082\u3060\u3051\u3067\u306a\u304f\u305d\u306e\u5b50\u5b6b\u306b\u3082\u53ca\u3073\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u305d\u306e\u3088\u3046\u306a\u751f\u547d\u3078\u306e\u4ecb\u5165\u3092\u884c\u3046\u3053\u3068\u306f\u8a8d\u3081\u3089\u308c\u308b\u306e\u304b\u3001\u8a8d\u3081\u3089\u308c\u308b\u3068\u3059\u308c\u3070\u305d\u306e\u6761\u4ef6\u306f\u4f55\u306a\u306e\u304b\u3001\u306a\u3069\u304c\u5e83\u304f\u8b70\u8ad6\u3055\u308c\u59cb\u3081\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u4eca\u56de\u306e\u4e2d\u56fd\u4eba\u7814\u7a76\u8005\u306e\u7814\u7a76\u306f\u8ad6\u6587\u3068\u3057\u3066\u516c\u958b\u3055\u308c\u3066\u3044\u306a\u3044\u305f\u3081\u3001\u5c02\u9580\u5bb6\u305f\u3061\u304c\u7cbe\u67fb\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u306a\u3044\u307e\u307e\u306a\u306e\u3067\u3059\u3002<\/p>\n<p>\u632f\u308a\u8fd4\u3063\u3066\u307f\u307e\u3057\u3087\u3046\u3002<\/p>\n<p>2018\u5e7411\u670825\u65e5\u3001\u30a6\u30a7\u30d6\u30e1\u30c7\u30a3\u30a2\u300e<a href=\"https:\/\/www.technologyreview.com\/s\/612458\/exclusive-chinese-scientists-are-creating-crispr-babies\/?fbclid=IwAR0u52_ZP4kGy1auPvmn6K8MR-8uNAACefBKm2oXH7AbNGGmWjSiSVinmZs\" target=\"_blank\" rel=\"noopener noreferrer\">MIT\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u30fb\u30ec\u30d3\u30e5\u30fc<\/a>\u300f\u304c\u300c\u30b9\u30af\u30fc\u30d7\u300d\u3068\u3057\u3066\u3001\u4e2d\u56fd\u306e\u6df1\u5733\u306b\u3042\u308b\u5357\u65b9\u79d1\u6280\u5927\u5b66\u306e\u8cc0\u5efa\u594e\uff08\u304c\u30fb\u3051\u3093\u3051\u3044\u3001\u30d5\u30fc\u30fb\u30b8\u30a7\u30f3\u30af\u30a4\uff09\u526f\u6559\u6388\u3089\u304c\u300cCRISPR\u30d9\u30d3\u30fc\u300d\u3092\u8a95\u751f\u3055\u305b\u3088\u3046\u3068\u3057\u3066\u3044\u308b\u3001\u3068\u5831\u3058\u307e\u3057\u305f\uff08CRISPR\u3068\u306f\u3001\u4ee3\u8868\u7684\u306a\u30b2\u30ce\u30e0\u7de8\u96c6\u6280\u8853\u300cCRISPR\/Cas9\uff08\u30af\u30ea\u30b9\u30d1\u30fc\u30fb\u30ad\u30e3\u30b9\uff19\uff09\u300d\u306e\u3053\u3068\u3067\u3059\uff09\u3002\u540c\u65e5\u3001\u8cc0\u81ea\u8eab\u304c<a href=\"https:\/\/youtu.be\/aezxaOn0efE\" target=\"_blank\" rel=\"noopener noreferrer\">\u30e6\u30fc\u30c1\u30e5\u30fc\u30d6<\/a>\u3067\u3001\u30b2\u30ce\u30e0\u3092\u7de8\u96c6\u3057\u305f\u8d64\u3061\u3083\u3093\u3092\u3059\u3067\u306b\u8a95\u751f\u3055\u305b\u305f\u3068\u8a9e\u308b\u52d5\u753b\u3092\u516c\u958b\u3057\u307e\u3057\u305f\u300211\u670826\u65e5\u306b\u306f\u3001<a href=\"https:\/\/www.apnews.com\/4997bb7aa36c45449b488e19ac83e86d?fbclid=IwAR1nyS9RcLP8327uvSw51YnXm7eeLVV7rSDpXNKw3AW08TOG0Wh3US1L8T4\" target=\"_blank\" rel=\"noopener noreferrer\">AP\u901a\u4fe1<\/a>\u304c\u3001\u8cc0\u526f\u6559\u6388\u3078\u306e\u30a4\u30f3\u30bf\u30d3\u30e5\u30fc\u3092\u8e0f\u307e\u3048\u3066\u3001\u540c\u69d8\u306e\u3053\u3068\u3092\u5831\u3058\u307e\u3057\u305f\u3002<\/p>\n<p>\u3068\u3053\u308d\u304c\u3001\u5357\u65b9\u79d1\u6280\u5927\u5b66\u306a\u3069\u95a2\u4fc2\u5404\u6a5f\u95a2\u306f\u3044\u3063\u305b\u3044\u306b\u3001\u81ea\u5206\u305f\u3061\u306f\u3053\u306e\u7814\u7a76\u306b\u95a2\u4e0e\u3057\u3066\u3044\u306a\u3044\u3001\u3068\u767a\u8868\u3057\u307e\u3057\u305f\u3002<\/p>\n<p>\u8cc0\u306f11\u670828\u65e5\u3001\u30b2\u30ce\u30e0\u7de8\u96c6\u306e\u79d1\u5b66\u3068\u502b\u7406\u306b\u3064\u3044\u3066\u5c02\u9580\u5bb6\u305f\u3061\u304c\u8b70\u8ad6\u3059\u308b\u4f1a\u8b70\u300c<a href=\"https:\/\/www.nationalacademies.org\/gene-editing\/2nd_summit\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u7b2c\uff12\u56de\u56fd\u969b\u30d2\u30c8\u30b2\u30ce\u30e0\u7de8\u96c6\u30b5\u30df\u30c3\u30c8<\/a>\u300d\u306b\u767b\u58c7\u3057\u3001\u81ea\u5206\u306e\u7814\u7a76\u306b\u3064\u3044\u3066\u767a\u8868\u3057\u307e\u3057\u305f\u3002<\/p>\n<div id=\"om-wxx776qo5w3etxr3cpps-holder\"><\/div>\n<p><script type=\"text\/javascript\" src=\"https:\/\/a.opmnstr.com\/app\/js\/api.min.js\" data-campaign=\"wxx776qo5w3etxr3cpps\" data-user=\"41855\" async><\/script><br \/>\n\u767a\u8868\u306b\u3088\u308b\u3068\u3001\u8cc0\u3089\u306f\u3001HIV\uff08\u30a8\u30a4\u30ba\u30a6\u30a4\u30eb\u30b9\uff09\u306b\u611f\u67d3\u3057\u3066\u3044\u308b\u7537\u6027\u306e\u7cbe\u5b50\u3068\u3001\u30d1\u30fc\u30c8\u30ca\u30fc\u306e\u5973\u6027\u306e\u5375\u5b50\u3092\u4f53\u5916\u53d7\u7cbe\u3055\u305b\u3066\u53d7\u7cbe\u5375\u3092\u3064\u304f\u308a\u3001\u305d\u306e\u300cCCR5\u300d\u3068\u3044\u3046\u907a\u4f1d\u5b50\u3092\u3001\u30b2\u30ce\u30e0\u7de8\u96c6\u6280\u8853\u300cCRISPR\/Cas9\u300d\u3067\u5207\u65ad\u3057\u307e\u3057\u305f\u3002CCR5\u306f\u3001HIV\u304c\u7d30\u80de\u306b\u4fb5\u5165\u3059\u308b\u3068\u304d\u306b\u5fc5\u8981\u306b\u306a\u308b\u300c\u53d7\u5bb9\u4f53\u300d\u3092\u6697\u53f7\u5316\u3057\u3066\u3044\u308b\u907a\u4f1d\u5b50\u3067\u3059\u3002\u3053\u308c\u304c\u50cd\u304b\u306a\u304f\u306a\u308b\u3068\u3001HIV\u306f\u305d\u306e\u7d30\u80de\u306b\u611f\u67d3\u3059\u308b\u3053\u3068\u304c\u96e3\u3057\u304f\u306a\u308a\u307e\u3059\u3002\u8cc0\u306f\u3001HIV\u306e\u60a3\u8005\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\u3067\u5e0c\u671b\u8005\u3092\u52df\u308a\u30017\u7d44\u306e\u30ab\u30c3\u30d7\u30eb\u304b\u3089\u53d7\u7cbe\u537531\u500b\u3092\u96c6\u3081\u305f\u3001\u3068\u8aac\u660e\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u3089\u306b\u30b2\u30ce\u30e0\u7de8\u96c6\u3092\u884c\u3063\u305f\u3068\u3053\u308d\u3001\u53cc\u5b50\u306e\u5973\u306e\u5b50\u3001\u300c\u30eb\u30eb\u300d\u3068\u300c\u30ca\u30ca\u300d\u304c\u8a95\u751f\u3057\u305f\u3068\u306e\u3053\u3068\u3067\u3057\u305f\u3002<\/p>\n<p>\u30b5\u30df\u30c3\u30c8\u3067\u306f\u3001\u591a\u304f\u306e\u5c02\u9580\u5bb6\u304b\u3089\u3001\u6cbb\u7642\u6cd5\u304c\u5b58\u5728\u3059\u308bHIV\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50\u3092\u7de8\u96c6\u5bfe\u8c61\u3068\u3059\u308b\u3053\u3068\u306e\u533b\u5b66\u7684\u6b63\u5f53\u6027\u3084\u3001\u3053\u3046\u3057\u305f\u7814\u7a76\u3067\u306f\u5fc5\u305a\u53d7\u3051\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u502b\u7406\u5be9\u67fb\u306a\u3069\u306b\u3064\u3044\u3066\u8cea\u554f\u304c\u76f8\u6b21\u304e\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u8cc0\u306f\u306f\u3063\u304d\u308a\u3068\u306f\u7b54\u3048\u305a\u3001\u4f1a\u8b70\u306e\u53c2\u52a0\u8005\u305f\u3061\u306f\u6e80\u8db3\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n<p>\u5c02\u9580\u5bb6\u305f\u3061\u304c\u3053\u306e\u7814\u7a76\u3092\u77e5\u308b\u305f\u3081\u306b\u53c2\u7167\u3067\u304d\u308b\u30c7\u30fc\u30bf\u306f\u3001\u3053\u306e\u30b5\u30df\u30c3\u30c8\u3067\u4f7f\u308f\u308c\u305f<a href=\"https:\/\/drive.google.com\/drive\/folders\/1T1zLTtHS2z_cgl29fN_7qJg7fLA4qlrd\" target=\"_blank\" rel=\"noopener noreferrer\">\u30d1\u30ef\u30fc\u30dd\u30a4\u30f3\u30c8\u30d5\u30a1\u30a4\u30eb<\/a>\uff08https:\/\/drive.google.com\/drive\/folders\/1T1zLTtHS2z_cgl29fN_7qJg7fLA4qlrd\uff09\u3060\u3051\u3067\u3059\u3002\u8cc0\u306f\u3001\u8ad6\u6587\u3092\u30b8\u30e3\u30fc\u30ca\u30eb\uff08\u5b66\u8853\u96d1\u8a8c\uff09\u306b\u6295\u7a3f\u4e2d\u3067\u3042\u308b\u3001\u3068\u30b5\u30df\u30c3\u30c8\u3067\u8a71\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u7814\u7a76\u304c\u672c\u5f53\u306b\u884c\u308f\u308c\u3066\u3044\u305f\u3068\u3057\u3066\u3001\u305d\u306e\u7d50\u679c\u306f\u3069\u306e\u3088\u3046\u306b\u516c\u8868\u3059\u308c\u3070\u3088\u3044\u306e\u3067\u3057\u3087\u3046\u304b\uff1f\u3000\u305d\u3082\u305d\u3082\u8ad6\u6587\u3068\u3057\u3066\u516c\u8868\u3059\u3079\u304d\u3067\u3057\u3087\u3046\u304b\uff1f<\/p>\n<p>\u5b66\u8853\u60c5\u5831\u30b5\u30a4\u30c8\u300e\u30ea\u30c8\u30e9\u30af\u30b7\u30e7\u30f3\u30a6\u30a9\u30c3\u30c1\u300f\u306e\u4e3b\u7b46\u3068\u3057\u3066\u3082\u77e5\u3089\u308c\u308b\u30b8\u30e3\u30fc\u30ca\u30ea\u30b9\u30c8\u3001\u30a2\u30c0\u30e0\u30fb\u30de\u30fc\u30ab\u30b9\u304c\u300e<a href=\"https:\/\/www.statnews.com\/2018\/12\/11\/should-journals-publish-crispr-babies-paper\/\" target=\"_blank\" rel=\"noopener noreferrer\">STAT<\/a>\u300f\u3067\u8ff0\u3079\u3066\u3044\u308b\u3068\u3053\u308d\u306b\u3088\u308c\u3070\u3001\u300e\u30b5\u30a4\u30a8\u30f3\u30b9\u300f\u306e\u7de8\u96c6\u8005\u306f\u3001\u8cc0\u306e\u8ad6\u6587\u539f\u7a3f\u3092\u53d7\u3051\u53d6\u3063\u305f\u304b\u3069\u3046\u304b\u306f\u7b54\u3048\u306a\u304b\u3063\u305f\u3082\u306e\u306e\u3001\u3053\u306e\u3088\u3046\u306b\u502b\u7406\u7684\u554f\u984c\u306e\u591a\u3044\u7814\u7a76\u3092\u691c\u8a0e\u3059\u308b\u53ef\u80fd\u6027\u306f\u4f4e\u3044\u3001\u3068\u306e\u3053\u3068\u3067\u3059\u3002\u307e\u305f\u3001\u300e\u7c73\u56fd\u533b\u5e2b\u4f1a\u30b8\u30e3\u30fc\u30ca\u30eb\uff08JAMA\uff09\u300f\u306e\u7de8\u96c6\u8005\u306f\u3001\u3084\u306f\u308a\u8cc0\u306e\u539f\u7a3f\u306b\u3064\u3044\u3066\u306f\u8a71\u3055\u306a\u3044\u3082\u306e\u306e\u3001\u7814\u7a76\u306f\u30e1\u30c7\u30a3\u30a2\u3067\u8a9e\u3089\u308c\u3066\u3044\u308b\u3053\u3068\u3060\u3051\u3067\u8a55\u4fa1\u3055\u308c\u308b\u3079\u304d\u3067\u306f\u306a\u3044\u3001\u3068\u540c\u8a8c\u306b\u30b3\u30e1\u30f3\u30c8\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u591a\u304f\u306e\u30b8\u30e3\u30fc\u30ca\u30eb\u306f\u3001\u502b\u7406\u5be9\u67fb\u3092\u7d4c\u3066\u3044\u306a\u3044\u7814\u7a76\u306e\u8ad6\u6587\u3092\u63b2\u8f09\u3059\u308b\u3053\u3068\u3092\u597d\u307e\u306a\u3044\u3068\u3044\u3046\u73fe\u5b9f\u304c\u3042\u308b\u4e00\u65b9\u3067\u3001\u79d1\u5b66\u7684\u306a\u8b70\u8ad6\u306f\u67fb\u8aad\u3092\u901a\u904e\u3057\u305f\u8ad6\u6587\u306b\u66f8\u304b\u308c\u3066\u3044\u308b\u3053\u3068\u306e\u307f\u3092\u524d\u63d0\u3068\u3057\u3066\u884c\u308f\u308c\u308b\u3079\u304d\u3001\u3068\u3044\u3046\u4e00\u822c\u8ad6\u3082\u307e\u305f\u8aac\u5f97\u529b\u3092\u6301\u3061\u307e\u3059\u3002<\/p>\n<p>\u307e\u305f\u30de\u30fc\u30ab\u30b9\u306f\u3001\u30b8\u30e3\u30fc\u30ca\u30eb\u306f\u502b\u7406\u7684\u554f\u984c\u304c\u3042\u308b\u7814\u7a76\u306e\u8ad6\u6587\u3092\u3042\u3048\u3066\u63b2\u8f09\u3059\u308b\u3053\u3068\u3082\u3042\u308b\u3001\u3068\u6307\u6458\u3057\u307e\u3059\u30022000\u5e74\u3001\u8457\u540d\u306a\u533b\u5b66\u8a8c\u300e\u30cb\u30e5\u30fc\u30a4\u30f3\u30b0\u30e9\u30f3\u30c9\u533b\u5b66\u96d1\u8a8c\u300f\u306f\u3001\u6570\u767e\u4eba\u3082\u306e\u30a6\u30ac\u30f3\u30c0\u4eba\u3092\u3001HIV\u304c\u611f\u67d3\u3057\u3066\u3044\u308b\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u6cbb\u7642\u3057\u306a\u3044\u307e\u307e\u89b3\u5bdf\u3057\u7d9a\u3051\u3001\u305d\u306e\u7d50\u679c\u3092\u307e\u3068\u3081\u305f<a href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJM200003303421303?query=recirc_curatedRelated_article\" target=\"_blank\" rel=\"noopener noreferrer\">\u8ad6\u6587<\/a>\u3092\u63b2\u8f09\u3059\u308b\u4e00\u65b9\u3067\u3001\u540c\u8a8c\u306e\u7de8\u96c6\u9577\u30de\u30fc\u30b7\u30e3\u30fb\u30a8\u30f3\u30b8\u30a7\u30eb\u304c<a href=\"https:\/\/www.philipalcabes.com\/wp-content\/uploads\/angell-editorial-nejm-2000.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">\u540c\u3058\u53f7\u306e\u793e\u8aac<\/a>\u3067\u305d\u306e\u7814\u7a76\u306e\u502b\u7406\u7684\u554f\u984c\u3092\u6307\u6458\u30fb\u6279\u5224\u3059\u308b\u3001\u3068\u3044\u3046\u3053\u3068\u304c\u3042\u308a\u307e\u3057\u305f\u3002\u30de\u30fc\u30ab\u30b9\u306f\u3001\u30b8\u30e3\u30fc\u30ca\u30eb\u3068\u3044\u3046\u3082\u306e\u306f\u4e00\u822c\u30e1\u30c7\u30a3\u30a2\u304b\u3089\u3067\u3042\u308d\u3046\u3068\u7814\u7a76\u8005\u304b\u3089\u3067\u3042\u308d\u3046\u3068\u3001\u6ce8\u76ee\u3055\u308c\u308b\u3053\u3068\u3092\u597d\u3080\u306e\u3060\u3001\u3068\u6307\u6458\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u307e\u305f\u3001\u30de\u30fc\u30ab\u30b9\u81ea\u8eab\u306f\u3001\u8cc0\u306e\u8ad6\u6587\u3092\u300c<a href=\"https:\/\/www.enago.jp\/academy\/preprint\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u30d7\u30ec\u30d7\u30ea\u30f3\u30c8<\/a>\u300d\u3068\u3057\u3066\u516c\u8868\u3059\u308b\u3053\u3068\u3092\u63d0\u6848\u3057\u3066\u3044\u307e\u3059\u3002\u30d7\u30ec\u30d7\u30ea\u30f3\u30c8\u3068\u306f\u3001\u30b8\u30e3\u30fc\u30ca\u30eb\u306b\u8ad6\u6587\u3068\u3057\u3066\u63b2\u8f09\u3055\u308c\u308b\u3053\u3068\u3092\u76ee\u7684\u306b\u66f8\u304b\u308c\u305f\u539f\u7a3f\u3067\u3001\u5b8c\u6210\u306f\u3057\u3066\u3044\u308b\u304c\u67fb\u8aad\u306f\u3055\u308c\u3066\u3044\u306a\u3044\u6bb5\u968e\u306e\u3082\u306e\u306e\u3053\u3068\u3092\u3044\u3044\u307e\u3059\u3002\u5b66\u8853\u754c\u3067\u306f\u3001\u3053\u306e\u30d7\u30ec\u30d7\u30ea\u30f3\u30c8\u3092\u3001\u300c\u30d7\u30ec\u30d7\u30ea\u30f3\u30c8\u30b5\u30fc\u30d0\u30fc\u300d\u306b\u30a2\u30c3\u30d7\u3057\u3066\u516c\u958b\u3059\u308b\u7fd2\u6163\u304c\u5e83\u304c\u3063\u3066\u3044\u307e\u3059\u3002\u30d7\u30ec\u30d7\u30ea\u30f3\u30c8\u30b5\u30fc\u30d0\u30fc\u306f\u3001\u7269\u7406\u5b66\u5206\u91ce\u306e\u300c<a href=\"https:\/\/arxiv.org\/\" target=\"_blank\" rel=\"noopener noreferrer\">arXiv<\/a>\u300d\u304c\u8001\u8217\u3067\u3059\u304c\u30012013\u5e74\u306b\u306f\u751f\u7269\u533b\u5b66\u5206\u91ce\u5c02\u9580\u306e\u300c<a href=\"https:\/\/www.biorxiv.org\/\" target=\"_blank\" rel=\"noopener noreferrer\">bioRxiv<\/a>\u300d\u3082\u8a2d\u7acb\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n<p>\u30d7\u30ec\u30d7\u30ea\u30f3\u30c8\u30b5\u30fc\u30d0\u30fc\u3067\u539f\u7a3f\u3092\u516c\u958b\u3059\u308c\u3070\u3001\u7279\u5b9a\u306e\u30b8\u30e3\u30fc\u30ca\u30eb\u304c\u8cac\u4efb\u3092\u6301\u3063\u3066\u304a\u58a8\u4ed8\u304d\u3092\u4e0e\u3048\u308b\u5fc5\u8981\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u533f\u540d\u306e\u67fb\u8aad\u8005\u306e\u4ee3\u308f\u308a\u306b\u3001\u5168\u4e16\u754c\u306e\u7814\u7a76\u8005\u3089\u304c\u516c\u958b\u306e\u5834\u3067\u3001\u67fb\u8aad\u3059\u308b\u3053\u3068\u306b\u306a\u308b\u3067\u3057\u3087\u3046\u3002\u305f\u3060\u3057\u8cc0\u81ea\u8eab\u306f\u3001\u8ad6\u6587\u304c\u30b8\u30e3\u30fc\u30ca\u30eb\u306b\u63b2\u8f09\u3055\u308c\u308b\u524d\u306b\u305d\u306e\u5185\u5bb9\u3092\u516c\u958b\u3059\u308b\u3053\u3068\u306f\u306a\u3044\u3001\u3068\u30b5\u30df\u30c3\u30c8\u3067\u8a9e\u3063\u305f\u3088\u3046\u3067\u3059\u3002<\/p>\n<p>\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u306a\u3069\u3092\u53d6\u308a\u4e0a\u3052\u308b\u30cb\u30e5\u30fc\u30b9\u30e1\u30c7\u30a3\u30a2\u300e<a href=\"https:\/\/www.wired.com\/story\/how-do-you-publish-the-work-of-a-scientific-villain\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u30ef\u30a4\u30a2\u30fc\u30c9<\/a>\u300f\u306b\u3088\u308c\u3070\u3001bioRxiv\u306f\u3001\u3069\u3093\u306a\u539f\u7a3f\u3067\u3082\u63b2\u8f09\u3059\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u3068\u3044\u3044\u307e\u3059\u3002\u4f8b\u3048\u3070\u30d2\u30c8\u3092\u5bfe\u8c61\u306b\u3057\u305f\u81e8\u5e8a\u8a66\u9a13\u306b\u3064\u3044\u3066\u306f\u3001\u7c73\u56fd\u306e\u300c<a href=\"https:\/\/clinicaltrials.gov\/\" target=\"_blank\" rel=\"noopener noreferrer\">ClinicalTrials.gov<\/a>\u300d\u306a\u3069\u3001\u4e8b\u524d\u767b\u9332\u3092\u7fa9\u52d9\u4ed8\u3051\u3089\u308c\u3066\u3044\u308b\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u306eID\u3092\u8a18\u3055\u306a\u3051\u308c\u3070\u306a\u3089\u306a\u3044\u3053\u3068\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002ID\u306f\u3001\u305d\u306e\u7814\u7a76\u304c\u502b\u7406\u5be9\u67fb\u3092\u7d4c\u305f\u3053\u3068\u3092\u793a\u3059\u3082\u306e\u3067\u3082\u3042\u308a\u307e\u3059\u3002\u8cc0\u306e\u7814\u7a76\u306f\u3001<a href=\"https:\/\/www.chictr.org.cn\/showprojen.aspx?proj=32758\" target=\"_blank\" rel=\"noopener noreferrer\">\u4e2d\u56fd\u306e\u81e8\u5e8a\u8a66\u9a13\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9<\/a>\u306b\u767b\u9332\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u304c\u3001\u305d\u308c\u306f\u5f53\u5c40\u306b\u3088\u308b\u627f\u8a8d\u3092\u5fc5\u8981\u3068\u3059\u308b\u3082\u306e\u3067\u306f\u306a\u3044\u3046\u3048\u3001\u767b\u9332\u3055\u308c\u305f\u65e5\u4ed8\u306f\u3053\u306e\u7814\u7a76\u304c\u59cb\u307e\u3063\u3066\u304b\u3089\u305a\u3044\u3076\u3093\u7d4c\u3063\u3066\u3044\u308b\u306f\u305a\u306e2018\u5e7411\u67088\u65e5\u3067\u3057\u305f\u3002<\/p>\n<p>bioRxiv\u306e\u5171\u540c\u8a2d\u7acb\u8005\u306f\u3001\u8cc0\u306e\u539f\u7a3f\u304c\u5c4a\u3044\u3066\u3044\u308b\u304b\u3069\u3046\u304b\u3092\u660e\u3089\u304b\u306b\u3057\u3066\u3044\u307e\u305b\u3093\u3002\u305d\u306e\u4e00\u65b9\u3067\u3001\u300c\u6211\u3005\u306e\u76ee\u7684\u306f\u3001\u975e\u502b\u7406\u7684\u306a\u7814\u7a76\u3092\u63a8\u85a6\u3057\u305f\u308a\u5968\u52b1\u3057\u305f\u308a\u3059\u308b\u3088\u3046\u306a\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u3092\u63d0\u4f9b\u3059\u308b\u3053\u3068\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u300d\u3068\u3001\u300e\u30ef\u30a4\u30a2\u30fc\u30c9\u300f\u3067\u8ff0\u3079\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u7b46\u8005\u3068\u3057\u3066\u306f\u3001\u3053\u308c\u307e\u3067\u3082\u502b\u7406\u7684\u3082\u3057\u304f\u306f\u79d1\u5b66\u7684\u306b\u554f\u984c\u306e\u3042\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306a\u7814\u7a76\u306e\u8ad6\u6587\u304c\u30b8\u30e3\u30fc\u30ca\u30eb\u306b\u63b2\u8f09\u3055\u308c\u305f\u3053\u3068\u306f\u4f55\u5ea6\u3082\u3042\u308b\u306e\u3067\u3001\u4eca\u56de\u3082\u6700\u7d42\u7684\u306b\u306f\u3001\u3069\u3053\u304b\u306e\u30b8\u30e3\u30fc\u30ca\u30eb\u304c\u63b2\u8f09\u3059\u308b\u306e\u3067\u306f\u306a\u3044\u304b\u3001\u3068\u63a8\u6e2c\u3057\u3066\u3044\u307e\u3059\u3002\u30de\u30fc\u30ab\u30b9\u306e\u6307\u6458\u901a\u308a\u3001\u3069\u3053\u304b\u306e\u30b8\u30e3\u30fc\u30ca\u30eb\u304c\u3001\u8868\u5411\u304d\u306b\u306f\u554f\u984c\u63d0\u8d77\u3068\u3044\u3046\u53e3\u5b9f\u3067\u3001\u5b9f\u969b\u306b\u306f\u8a71\u984c\u3065\u304f\u308a\u306e\u305f\u3081\u306b\uff08\uff1f\uff09\u3001\u8cc0\u3089\u306e\u8ad6\u6587\u3092\u63b2\u8f09\u3059\u308b\u53ef\u80fd\u6027\u306f\u3042\u308b\u3067\u3057\u3087\u3046\u3002<\/p>\n<p>\u307e\u305f\u4eca\u56de\u306e\u4ef6\u306b\u5fdc\u3058\u3066\u3001\u4e2d\u56fd\u306e\u79d1\u5b66\u6280\u8853\u7701\u3084\u8cc0\u304c\u5c5e\u3057\u3066\u3044\u308b\u5357\u65b9\u79d1\u6280\u5927\u5b66\u3001\u304b\u3064\u3066\u5c5e\u3057\u3066\u3044\u305f\u30e9\u30a4\u30b9\u5927\u5b66\u306f\u3001\u6cd5\u4ee4\u306b\u9055\u53cd\u3057\u3066\u3044\u306a\u3044\u304b\u3069\u3046\u304b\u306a\u3069\u8abf\u67fb\u3092\u9032\u3081\u3066\u3044\u308b\u3068\u4f1d\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n<p>\u3044\u305a\u308c\u306b\u305b\u3088\u3001\u8cc0\u3089\u306e\u8a66\u307f\u306f\u3001\u79d1\u5b66\u7684\u306b\u3082\u502b\u7406\u7684\u306b\u3082\u771f\u5263\u306b\u8ad6\u3058\u308b\u3079\u304d\u8ad6\u70b9\u3092\u6570\u591a\u304f\u542b\u3080\u3082\u306e\u3067\u3059\u306e\u3067\u3001\u5c11\u3057\u3067\u3082\u591a\u304f\u306e\u4e8b\u5b9f\u304c\u660e\u3089\u304b\u306b\u3055\u308c\u3001\u8abf\u67fb\u5831\u544a\u66f8\u306a\u3069\u304c\u3059\u307f\u3084\u304b\u306b\u516c\u958b\u3055\u308c\u308b\u3053\u3068\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u672c\u8a8c\u3067\u3082\u304a\u4f1d\u3048\u3057\u3066\u3044\u308b\u901a\u308a\u30012018\u5e7411\u6708\u672b\u3001\u4e2d\u56fd\u306e\u7814\u7a76\u8005\u304c\u3001\u30d2\u30c8\u306e\u53d7\u7cbe\u5375\u306b\u300c\u30b2\u30ce\u30e0\u7de8\u96c6\u300d\u3092\u884c\u3063\u3066\u3001\u907a\u4f1d\u5b50\u3092\u6539\u5909\u3055\u305b\u305f\u8d64\u3061\u3083\u3093\u3092\u8a95\u751f\u3055\u305b\u305f\u3068\u767a\u8868\u3057\u3001\u4e16\u754c\u3092\u9a12\u7136\u3068\u3055\u305b\u307e\u3057\u305f\u3002\u30b2\u30ce\u30e0\u7de8\u96c6\u3068\u306f\u3001\u307e\u308b\u3067\u6587\u7ae0\u3092\u30ef\u30fc\u30c9\u3067\u66f8\u304d\u63db\u3048\u308b\u3088\u3046\u306b\u3001\u907a\u4f1d\u5b50\u304c\u542b\u307e\u308c\u3066\u3044\u308bDNA\u3092\u5207\u308a\u8cbc\u308a\u3059\u308b\u6280\u8853\u306e\u3053\u3068\u3067\u3059\u3002\u3072\u3068\u6614\u524d\u306e\u300c\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u6280\u8853\u300d\u306b\u6bd4\u3079\u308b\u3068\u3001\u6b63\u78ba\u3055\u3082\u6210\u529f\u7387\u3082\u683c\u6bb5\u306b\u9ad8\u3044\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u30b2\u30ce\u30e0\u7de8\u96c6\u3092\u3001\u4eba\u9593\u306e\u300c\u4f53\u7d30\u80de\u300d\u3067\u306f\u306a\u304f\u300c\u53d7\u7cbe\u5375\u300d\u306a\u3069\u306b\u884c\u3048\u3070\u3001\u7de8\u96c6\u306e\u7d50\u679c\u306f\u751f\u307e\u308c\u3066\u304f\u308b\u5b50\u3069\u3082\u3060\u3051\u3067\u306a\u304f\u305d\u306e\u5b50\u5b6b\u306b\u3082\u53ca\u3073\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u305d\u306e\u3088\u3046\u306a\u751f\u547d\u3078\u306e\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2018\u5e7411\u670825\u65e5\u3001\u30a6\u30a7\u30d6\u30e1\u30c7\u30a3\u30a2\u300eMIT\u30c6\u30af\u30ce\u30ed\u30b8\u30fc\u30fb\u30ec\u30d3\u30e5\u30fc\u300f\u304c\u300c\u30b9\u30af\u30fc\u30d7\u300d\u3068\u3057\u3066\u3001\u4e2d\u56fd\u306e\u6df1\u5733\u306b\u3042\u308b\u5357\u65b9\u79d1\u6280\u5927\u5b66\u306e\u8cc0\u5efa\u594e\uff08\u304c\u30fb\u3051\u3093\u3051\u3044\u3001\u30d5\u30fc\u30fb\u30b8\u30a7\u30f3\u30af\u30a4\uff09\u526f\u6559\u6388\u3089\u304c\u300cCRISPR\u30d9\u30d3\u30fc\u300d\u3092\u8a95\u751f\u3055\u305b\u3088\u3046\u3068\u3057\u3066\u3044\u308b\u3001\u3068\u5831\u3058\u307e\u3057\u305f\uff08CRISPR\u3068\u306f\u3001\u4ee3\u8868\u7684\u306a\u30b2\u30ce\u30e0\u7de8\u96c6\u6280\u8853\u300cCRISPR\/Cas9\uff08\u30af\u30ea\u30b9\u30d1\u30fc\u30fb\u30ad\u30e3\u30b9\uff19\uff09\u300d\u306e\u3053\u3068\u3067\u3059\uff09\u3002\u540c\u65e5\u3001\u8cc0\u81ea\u8eab\u304c\u30e6\u30fc\u30c1\u30e5\u30fc\u30d6\u3067\u3001\u30b2\u30ce\u30e0\u3092\u7de8\u96c6\u3057\u305f\u8d64\u3061\u3083\u3093\u3092\u3059\u3067\u306b\u8a95\u751f\u3055\u305b\u305f\u3068\u8a9e\u308b\u52d5\u753b\u3092\u516c\u958b\u3057\u307e\u3057\u305f\u300211\u670826\u65e5\u306b\u306f\u3001AP\u901a\u4fe1\u304c\u3001\u8cc0\u526f\u6559\u6388\u3078\u306e\u30a4\u30f3\u30bf\u30d3\u30e5\u30fc\u3092\u8e0f\u307e\u3048\u3066\u3001\u540c\u69d8\u306e\u3053\u3068\u3092\u5831\u3058\u307e\u3057\u305f\u3002 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