{"id":505,"date":"2015-05-18T16:17:31","date_gmt":"2015-05-18T07:17:31","guid":{"rendered":"http:\/\/www.enago-academy.com\/?p=505"},"modified":"2021-02-17T15:23:11","modified_gmt":"2021-02-17T06:23:11","slug":"open-access-internet","status":"publish","type":"post","link":"https:\/\/www.enago.com\/academy\/jp\/open-access-internet\/","title":{"rendered":"\u300c\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u300d\u306e\u201c\u30aa\u30fc\u30d7\u30f3\u5ea6\u201d\u306e\u9055\u3044"},"content":{"rendered":"<table width=\"243\">\n<tbody>\n<tr>\n<td width=\"243\">\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u306e\u7a2e\u985e<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>\u30a4\u30f3\u30bf\u30fc\u30cd\u30c3\u30c8\u4e0a\u3067\u516c\u8868\u3055\u308c\u3001\u8ab0\u3082\u304c\u7121\u6599\u3067\u8aad\u3080\u3053\u3068\u306e\u3067\u304d\u308b\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u30fb\u30b8\u30e3\u30fc\u30ca\u30eb\u3002\u8fd1\u5e74\u3001\u305d\u306e\u5b58\u5728\u610f\u7fa9\u304c\u6ce8\u76ee\u3055\u308c\u7d9a\u3051\u3066\u3044\u307e\u3059\u304c\u3001\u5b9f\u306f\u3001\u305d\u306e\u300c\u30aa\u30fc\u30d7\u30f3\u300d\u5ea6\u306b\u306f\u304b\u306a\u308a\u306e\u5dee\u304c\u307f\u3089\u308c\u307e\u3059\u3002\u4eca\u56de\u306f\u3001\u3088\u304f\u3042\u308b\u30bf\u30a4\u30d7\u3092\u3044\u304f\u3064\u304b\u3042\u3052\u3066\u307f\u307e\u3059\u3002\u53c2\u8003\u6587\u732e\u3092\u63a2\u3059\u3068\u304d\u3001\u307e\u305f\u306f\u81ea\u5206\u306e\u8ad6\u6587\u3092\u767a\u8868\u3059\u308b\u30b8\u30e3\u30fc\u30ca\u30eb\u3092\u63a2\u3059\u3068\u304d\u306b\u3001\u53c2\u8003\u306b\u3057\u3066\u304f\u3060\u3055\u3044\u3002<br \/>\n<strong>1.\u5b8c\u5168\u306b\u30aa\u30fc\u30d7\u30f3\u306a\u3082\u306e<\/strong><br \/>\n\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u30fb\u30b8\u30e3\u30fc\u30ca\u30eb\u3068\u3044\u3046\u3068\u3001\u591a\u304f\u306e\u4eba\u304c\u60f3\u50cf\u3059\u308b\u306e\u304c\u3053\u306e\u30bf\u30a4\u30d7\u306e\u96d1\u8a8c\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\uff1f\u3000\u5b9f\u969b\u306b\u3001\u8fd1\u5e74\u5275\u520a\u3055\u308c\u305f\u65b0\u3057\u3044\u30b8\u30e3\u30fc\u30ca\u30eb\u306b\u306f\u3001\u96d1\u8a8c\u306e\u5185\u5bb9\u3092\u305d\u306e\u5dfb\u982d\u304b\u3089\u5dfb\u672b\u307e\u3067\u3001\u3059\u3079\u3066\u30aa\u30f3\u30e9\u30a4\u30f3\u3067\u95b2\u89a7\u3067\u304d\u308b\u3088\u3046\u306b\u3057\u3066\u3044\u308b\u3082\u306e\u304c\u5c11\u306a\u304f\u3042\u308a\u307e\u305b\u3093\u3002<a href=\"https:\/\/www.plos.org\/\" target=\"_blank\" rel=\"noopener noreferrer\">Plos<\/a>\u3084<a href=\"https:\/\/www.biomedcentral.com\/\" target=\"_blank\" rel=\"noopener noreferrer\">BioMedCentral<\/a>\u304c\u767a\u884c\u3059\u308b\u30b8\u30e3\u30fc\u30ca\u30eb\u306e\u307b\u3068\u3093\u3069\u304c\u3053\u308c\u306b\u5f53\u305f\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u96d1\u8a8c\u767a\u884c\u306e\u305f\u3081\u306e\u904b\u55b6\u8cbb\u3092\u78ba\u4fdd\u3059\u308b\u3053\u3068\u306a\u3069\u3092\u7406\u7531\u306b\u3001\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u30fb\u30b8\u30e3\u30fc\u30ca\u30eb\u3068\u3044\u308f\u308c\u308b\u3053\u3068\u306f\u3042\u308b\u3082\u306e\u306e\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5236\u9650\u3092\u8a2d\u3051\u3066\u3044\u308b\u30b1\u30fc\u30b9\u3082\u307f\u3089\u308c\u307e\u3059\u3002<br \/>\n<strong>2.\u6295\u7a3f\u3055\u308c\u305f\u7814\u7a76\u8ad6\u6587\u306e\u307f\u30aa\u30fc\u30d7\u30f3\u306a\u3082\u306e<\/strong><br \/>\n\u6295\u7a3f\u3055\u308c\u305f\u7814\u7a76\u8ad6\u6587\u306e\u307f\u95b2\u89a7\u3067\u304d\u3001\u65b0\u3057\u3044\u51fa\u7248\u7269\u306e\u30ec\u30d3\u30e5\u30fc\u306a\u3069\u3001\u8ad6\u6587\u4ee5\u5916\u306e\u63b2\u8f09\u8a18\u4e8b\u3078\u306e\u30a2\u30af\u30bb\u30b9\u3092\u5236\u9650\u3059\u308b\u30bf\u30a4\u30d7\u3067\u3059\u3002\u81ea\u5206\u306e\u7814\u7a76\u306b\u95a2\u4fc2\u306e\u3042\u308b\u6700\u65b0\u306e\u7814\u7a76\u7d50\u679c\u3092\u63a2\u3059\u306e\u306b\u306f\u3001\u3053\u308c\u3067\u5341\u5206\u3067\u3057\u3087\u3046\u3002<br \/>\n<strong>3.\u6295\u7a3f\u3055\u308c\u305f\u7814\u7a76\u8ad6\u6587\u306e\u4e00\u90e8\u306e\u307f\u30aa\u30fc\u30d7\u30f3\u3067\u3001\u4ed6\u306e\u8ad6\u6587\u306b\u306f\u30a2\u30af\u30bb\u30b9\u3067\u304d\u306a\u3044\u3082\u306e<\/strong><br \/>\n\u9650\u3089\u308c\u305f\u7814\u7a76\u8ad6\u6587\u306e\u307f\u30aa\u30f3\u30e9\u30a4\u30f3\u3067\u7121\u6599\u95b2\u89a7\u3067\u304d\u308b\u3068\u3044\u3046\u30bf\u30a4\u30d7\u3067\u3059\u3002\u95a2\u5fc3\u306e\u3042\u308b\u8ad6\u6587\u304c\u305f\u307e\u305f\u307e\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u306b\u306a\u3063\u3066\u3044\u308c\u3070\u3044\u3044\u306e\u3067\u3059\u304c\u3001\u305d\u3046\u3067\u306a\u3051\u308c\u3070\u3001\u4eca\u307e\u3067\u3069\u304a\u308a\u306b\u96d1\u8a8c\u3092\u8cfc\u5165\u3057\u306a\u3051\u308c\u3070\u95b2\u89a7\u3067\u304d\u307e\u305b\u3093\u3002\u3069\u306e\u8ad6\u6587\u304c\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u306b\u306a\u308b\u304b\u306f\u3001\u8ad6\u6587\u306e\u7b46\u8005\u3067\u306f\u306a\u304f\u96d1\u8a8c\u306e\u7de8\u96c6\u8005\u304c\u6c7a\u3081\u308b\u5834\u5408\u304c\u591a\u3044\u3088\u3046\u3067\u3059\u306e\u3067\u3001\u3053\u306e\u3088\u3046\u306a\u96d1\u8a8c\u306b\u6295\u7a3f\u3059\u308b\u5834\u5408\u306f\u3001\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u306e\u9078\u51fa\u65b9\u6cd5\u3092\u4e8b\u524d\u306b\u7de8\u96c6\u8005\u306b\u78ba\u8a8d\u3057\u305f\u307b\u3046\u304c\u3088\u3044\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002<br \/>\n\u307e\u305f\u3001\u300c\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u30fb\u30aa\u30d7\u30b7\u30e7\u30f3\u300d\u3068\u3044\u3063\u3066\u3001\u6295\u7a3f\u8005\u304c1000\u30c9\u30eb\u304b\u30893000\u30c9\u30eb\u7a0b\u5ea6\u306e\u63b2\u8f09\u6599\u3092\u6255\u3046\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u81ea\u5206\u306e\u8ad6\u6587\u3092\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u306b\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u30b8\u30e3\u30fc\u30ca\u30eb\u3082\u3042\u308a\u307e\u3059\u3002<br \/>\n\u3053\u306e\u3088\u3046\u306b\u7279\u5b9a\u306e\u8ad6\u6587\u3060\u3051\u304c\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u5316\u3055\u308c\u3066\u3044\u308b\u30b8\u30e3\u30fc\u30ca\u30eb\u3092\u300c<a href=\"https:\/\/current.ndl.go.jp\/ca1684\" target=\"_blank\" rel=\"noopener noreferrer\">\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9\u30fb\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u30fb\u30b8\u30e3\u30fc\u30ca\u30eb<\/a>\u300d\u3068\u547c\u3076\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002<\/p>\n<div id=\"om-ka2bx95umm5zappy9ndp-holder\"><\/div>\n<p>\u6700\u8fd1\u306e\u50be\u5411\u3068\u3057\u3066\u306f\u3001\u793e\u4f1a\u7684\u306b\u95a2\u5fc3\u304c\u9ad8\u3044\u8ad6\u6587\u306f\u3001\u63b2\u8f09\u8a8c\u304c\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u30fb\u30b8\u30e3\u30fc\u30ca\u30eb\u3067\u306a\u304f\u3066\u3082\u3001\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u5316\u3055\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u3088\u3046\u3067\u3059\u3002\u4eac\u90fd\u5927\u5b66\u306e\u5c71\u4e2d\u4f38\u5f25\u6559\u6388\u304ciPS\u7d30\u80de\u306e\u4f5c\u6210\u6210\u529f\u30922006\u5e74\u306b\u5831\u544a\u3057\u305f<a href=\"https:\/\/www.cell.com\/abstract\/S0092-8674%2806%2900976-7\" target=\"_blank\" rel=\"noopener noreferrer\">\u8ad6\u6587<\/a>\u306f\u3001\u300e\u30bb\u30eb\uff08cell\uff09\u300f\u3067\u521d\u3081\u304b\u3089\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u5316\u3055\u308c\u3066\u516c\u958b\u3055\u308c\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u5c0f\u4fdd\u65b9\u6674\u5b50\u30fb\u7406\u5316\u5b66\u7814\u7a76\u6240\u30e6\u30cb\u30c3\u30c8\u30ea\u30fc\u30c0\u30fc\uff08\u5f53\u6642\uff09\u304c\u300cSTAP\u7d30\u80de\u300d\u306e\u4f5c\u6210\u6210\u529f\u30922014\u5e74\u306b\u300e\u30cd\u30a4\u30c1\u30e3\u30fc\u300f\u3067\u5831\u544a\u3057\u305f<a href=\"https:\/\/www.nature.com\/nature\/journal\/v505\/n7485\/full\/nature12969.html\" target=\"_blank\" rel=\"noopener noreferrer\">\u8ad6\u6587<\/a>\u306f\u3001\u5f53\u521d\u306f\u8cfc\u8aad\u8005\u3057\u304b\u8aad\u3081\u307e\u305b\u3093\u3067\u3057\u305f\u304c\u3001\u7814\u7a76\u4e0d\u6b63\u304c\u7591\u308f\u308c\u3001\u4e16\u9593\u306e\u6ce8\u76ee\u304c\u96c6\u307e\u3063\u3066\u304b\u3089\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u5316\u3055\u308c\u307e\u3057\u305f\u3002<br \/>\n<strong>\u767a\u884c\u5f53\u521d\u306f\u6295\u7a3f\u3055\u308c\u305f\u7814\u7a76\u8ad6\u6587\u306e\u4e00\u90e8\u306e\u307f\u30aa\u30fc\u30d7\u30f3\u3067\u3001\u5f8c\u65e5\u3001\u3059\u3079\u3066\u306e\u8ad6\u6587\u306b\u30a2\u30af\u30bb\u30b9\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308b\u3082\u306e<\/strong><br \/>\n\u524d\u8ff0\u306e\u30bf\u30a4\u30d7\u3068\u4f3c\u3066\u3044\u307e\u3059\u304c\u3001\u96d1\u8a8c\u306e\u767a\u884c\u5f53\u6642\u306b\u306f\u81ea\u7531\u306b\u95b2\u89a7\u3067\u304d\u306a\u304b\u3063\u305f\u8ad6\u6587\u304c\u3001\u4e00\u5b9a\u671f\u9593\u3092\u7d4c\u3066\u3059\u3079\u3066\u95b2\u89a7\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308b\u3068\u3044\u3046\u70b9\u304c\u9055\u3044\u307e\u3059\u3002\u3053\u306e\u30bf\u30a4\u30d7\u306e\u30b8\u30e3\u30fc\u30ca\u30eb\u3067\u306f\u3001\uff11\u5e74\u304b\u3089\u6570\u5e74\u4ee5\u4e0a\u7d4c\u3063\u305f\u53e4\u3044\u53f7\u304c\u516c\u958b\u5bfe\u8c61\u3068\u306a\u308b\u5834\u5408\u304c\u591a\u3044\u3088\u3046\u3067\u3059\u3002\u3069\u306e\u304f\u3089\u3044\u306e\u671f\u9593\u3092\u7d4c\u3066\u30aa\u30fc\u30d7\u30f3\u306b\u306a\u308b\u304b\u306f\u30b8\u30e3\u30fc\u30ca\u30eb\u306b\u3088\u3063\u3066\u9055\u3044\u307e\u3059\u306e\u3067\u3001\u6700\u65b0\u306e\u8ad6\u6587\u3092\u63a2\u3059\u3068\u304d\u3084\u81ea\u5206\u306e\u8ad6\u6587\u3092\u6295\u7a3f\u3059\u308b\u3055\u3044\u306b\u306f\u3001\u305d\u306e\u70b9\u306b\u5341\u5206\u6c17\u3092\u3064\u3051\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<br \/>\n<strong>\u767a\u884c\u5f53\u521d\u306f\u30aa\u30fc\u30d7\u30f3\u3067\u306a\u3044\u3082\u306e\u306e\u3001\u5c11\u3057\u9045\u308c\u3066\u96d1\u8a8c\u5168\u4f53\u304c\u30aa\u30fc\u30d7\u30f3\u306b\u306a\u308b\u3082\u306e<\/strong><br \/>\n\u6700\u65b0\u306e\u8ad6\u6587\u306f\u8cfc\u8aad\u8005\u3057\u304b\u8aad\u3081\u306a\u304f\u3066\u3082\u3001\u4e00\u5b9a\u306e\u671f\u9593\u3092\u7d4c\u3066\u3001\u30b8\u30e3\u30fc\u30ca\u30eb\u5168\u4f53\u304c\u3059\u3079\u3066\u7121\u6599\u3067\u95b2\u89a7\u3067\u304d\u308b\u3088\u3046\u306b\u306a\u308b\u30bf\u30a4\u30d7\u3067\u3001\u9577\u5e74\u306b\u308f\u305f\u3063\u3066\u767a\u884c\u3092\u7d9a\u3051\u3066\u3044\u308b\u5b66\u4f1a\u8a8c\u306b\u591a\u304f\u898b\u3089\u308c\u308b\u3088\u3046\u3067\u3059\u3002\u3053\u3061\u3089\u3082\u4e0a\u8ff0\u306e\u30bf\u30a4\u30d7\u3068\u540c\u69d8\u306b\u3001\u3069\u306e\u304f\u3089\u3044\u306e\u671f\u9593\u3092\u7d4c\u3066\u30aa\u30fc\u30d7\u30f3\u306b\u306a\u308b\u304b\u306f\u30b8\u30e3\u30fc\u30ca\u30eb\u306b\u3088\u3063\u3066\u9055\u3044\u307e\u3059\u3002<br \/>\n\u305f\u3068\u3048\u3070\u3001<a>\u30a2\u30e1\u30ea\u30ab\u5fae\u751f\u7269\u5b66\u4f1a\uff08ASM: American Society for Microbiology\uff09<\/a>\u306e\u767a\u884c\u3059\u308b\u96d1\u8a8c\u306e\u8ad6\u6587\u306f\u767a\u884c\uff14\u30ab\u6708\u5f8c\u306b\u3001<a href=\"https:\/\/www.cshlpress.com\/\" target=\"_blank\" rel=\"noopener noreferrer\">\u30b3\u30fc\u30eb\u30c9\u30b9\u30d7\u30ea\u30f3\u30b0\u30cf\u30fc\u30d0\u30fc\u7814\u7a76\u6240\u51fa\u7248\uff08Cold Spring Harbor Laboratory Press\uff09<\/a>\u306e\u767a\u884c\u3059\u308b\u96d1\u8a8c\u306e\u8ad6\u6587\u306f\uff16\u30ab\u6708\u5f8c\u306b\u7121\u6599\u516c\u958b\u3068\u306a\u308a\u307e\u3059\u3002<br \/>\n<strong>\u96d1\u8a8c\u81ea\u4f53\u306f\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u3067\u306f\u306a\u3044\u304c\u3001\u96d1\u8a8c\u306b\u63b2\u8f09\u3055\u308c\u305f\u8ad6\u6587\u3092\u8457\u8005\u304c\u4f55\u3089\u304b\u306e\u5f62\u3067\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u306b\u3059\u308b\u3053\u3068\u3092\u8a31\u53ef\u3057\u3066\u3044\u308b\u3082\u306e<\/strong><br \/>\n\u4eca\u307e\u3067\u306f\u3001\u6295\u7a3f\u3057\u305f\u8ad6\u6587\u304c\u5b66\u4f1a\u8a8c\u306b\u8f09\u308b\u3068\u3001\u540c\u3058\u8ad6\u6587\u3092\u4ed6\u306e\u5834\u6240\u306b\u63b2\u8f09\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u3057\u304b\u3057\u6628\u4eca\u3001\u305d\u306e\u30b8\u30e3\u30fc\u30ca\u30eb\u81ea\u4f53\u306f\u30aa\u30fc\u30d7\u30f3\u3067\u306f\u306a\u3044\u3082\u306e\u306e\u3001\u7814\u7a76\u8005\u672c\u4eba\u304c\u63a1\u7528\u3055\u308c\u305f\u81ea\u5206\u306e\u8ad6\u6587\u3092\u3001\u4ed6\u306e\u30aa\u30fc\u30d7\u30f3\u30fb\u30a2\u30af\u30bb\u30b9\u30fb\u30a6\u30a7\u30d6\u30b5\u30a4\u30c8\u306b\u63b2\u8f09\u3059\u308b\u3053\u3068\u3092\u8a31\u53ef\u3059\u308b\u30b1\u30fc\u30b9\u304c\u307f\u3089\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u3066\u304d\u307e\u3057\u305f\u3002<br \/>\n\u30a4\u30f3\u30bf\u30fc\u30cd\u30c3\u30c8\u3067\u5148\u884c\u7814\u7a76\u3092\u898b\u3064\u3051\u308b\u305f\u3081\u306b\u8ad6\u6587\u3092\u63a2\u3059\u3068\u304d\u3001\u300c\u3042\u3042\u3001\u3053\u306e\u8ad6\u6587\u306f\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u3058\u3083\u306a\u3044\u3093\u3060\u300d\u3068\u3059\u3050\u306b\u8ae6\u3081\u305a\u3001\u4ed6\u306e\u6240\u306b\u63b2\u8f09\u3055\u308c\u3066\u3044\u306a\u3044\u304b\u63a2\u3057\u3066\u307f\u307e\u3057\u3087\u3046\u3002<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/\" target=\"_blank\" rel=\"noopener noreferrer\">PubMed Central<\/a>\u3084<a href=\"https:\/\/www.sciencedirect.com\/\" target=\"_blank\" rel=\"noopener noreferrer\">ScienceDirect<\/a>\u7d4c\u7531\u3067\u8aad\u3080\u3053\u3068\u304c\u3067\u304d\u308b\u5834\u5408\u3082\u3042\u308c\u3070\u3001\u8457\u8005\u306e\u5927\u5b66\u3084\u7814\u7a76\u5ba4\u306e\u30a6\u30a7\u30d6\u30b5\u30a4\u30c8\u306b\u30a2\u30c3\u30d7\u30ed\u30fc\u30c9\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002\u4e2d\u306b\u306f\u3001\u539f\u8457\u8ad6\u6587\u306f\u8cfc\u8aad\u8005\u3057\u304b\u30a2\u30af\u30bb\u30b9\u3067\u304d\u306a\u3044\u306e\u306b\u3001\u306a\u305c\u304b\u7ffb\u8a33\u3055\u308c\u305f\u3082\u306e\u304cPDF\u30d5\u30a1\u30a4\u30eb\u306b\u306a\u3063\u3066\u3001\u533b\u7642\u95a2\u4fc2\u4f01\u696d\u306e\u30a6\u30a7\u30d6\u30b5\u30a4\u30c8\u3067\u7121\u6599\u516c\u958b\u3055\u308c\u3066\u3044\u308b\u30fb\u30fb\u30fb\u3068\u3044\u3046\u3053\u3068\u3082\u3002\u6839\u6c17\u3088\u304f\u63a2\u3057\u307e\u3057\u3087\u3046\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u306e\u7a2e\u985e \u30a4\u30f3\u30bf\u30fc\u30cd\u30c3\u30c8\u4e0a\u3067\u516c\u8868\u3055\u308c\u3001\u8ab0\u3082\u304c\u7121\u6599\u3067\u8aad\u3080\u3053\u3068\u306e\u3067\u304d\u308b\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u30fb\u30b8\u30e3\u30fc\u30ca\u30eb\u3002\u8fd1\u5e74\u3001\u305d\u306e\u5b58\u5728\u610f\u7fa9\u304c\u6ce8\u76ee\u3055\u308c\u7d9a\u3051\u3066\u3044\u307e\u3059\u304c\u3001\u5b9f\u306f\u3001\u305d\u306e\u300c\u30aa\u30fc\u30d7\u30f3\u300d\u5ea6\u306b\u306f\u304b\u306a\u308a\u306e\u5dee\u304c\u307f\u3089\u308c\u307e\u3059\u3002\u4eca\u56de\u306f\u3001\u3088\u304f\u3042\u308b\u30bf\u30a4\u30d7\u3092\u3044\u304f\u3064\u304b\u3042\u3052\u3066\u307f\u307e\u3059\u3002\u53c2\u8003\u6587\u732e\u3092\u63a2\u3059\u3068\u304d\u3001\u307e\u305f\u306f\u81ea\u5206\u306e\u8ad6\u6587\u3092\u767a\u8868\u3059\u308b\u30b8\u30e3\u30fc\u30ca\u30eb\u3092\u63a2\u3059\u3068\u304d\u306b\u3001\u53c2\u8003\u306b\u3057\u3066\u304f\u3060\u3055\u3044\u3002 1.\u5b8c\u5168\u306b\u30aa\u30fc\u30d7\u30f3\u306a\u3082\u306e \u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u30fb\u30b8\u30e3\u30fc\u30ca\u30eb\u3068\u3044\u3046\u3068\u3001\u591a\u304f\u306e\u4eba\u304c\u60f3\u50cf\u3059\u308b\u306e\u304c\u3053\u306e\u30bf\u30a4\u30d7\u306e\u96d1\u8a8c\u3067\u306f\u306a\u3044\u3067\u3057\u3087\u3046\u304b\uff1f\u3000\u5b9f\u969b\u306b\u3001\u8fd1\u5e74\u5275\u520a\u3055\u308c\u305f\u65b0\u3057\u3044\u30b8\u30e3\u30fc\u30ca\u30eb\u306b\u306f\u3001\u96d1\u8a8c\u306e\u5185\u5bb9\u3092\u305d\u306e\u5dfb\u982d\u304b\u3089\u5dfb\u672b\u307e\u3067\u3001\u3059\u3079\u3066\u30aa\u30f3\u30e9\u30a4\u30f3\u3067\u95b2\u89a7\u3067\u304d\u308b\u3088\u3046\u306b\u3057\u3066\u3044\u308b\u3082\u306e\u304c\u5c11\u306a\u304f\u3042\u308a\u307e\u305b\u3093\u3002Plos\u3084BioMedCentral\u304c\u767a\u884c\u3059\u308b\u30b8\u30e3\u30fc\u30ca\u30eb\u306e\u307b\u3068\u3093\u3069\u304c\u3053\u308c\u306b\u5f53\u305f\u308a\u307e\u3059\u3002\u3057\u304b\u3057\u96d1\u8a8c\u767a\u884c\u306e\u305f\u3081\u306e\u904b\u55b6\u8cbb\u3092\u78ba\u4fdd\u3059\u308b\u3053\u3068\u306a\u3069\u3092\u7406\u7531\u306b\u3001\u30aa\u30fc\u30d7\u30f3\u30a2\u30af\u30bb\u30b9\u30fb\u30b8\u30e3\u30fc\u30ca\u30eb\u3068\u3044\u308f\u308c\u308b\u3053\u3068\u306f\u3042\u308b\u3082\u306e\u306e\u3001\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5236\u9650\u3092\u8a2d\u3051\u3066\u3044\u308b\u30b1\u30fc\u30b9\u3082\u307f\u3089\u308c\u307e\u3059\u3002 2.\u6295\u7a3f\u3055\u308c\u305f\u7814\u7a76\u8ad6\u6587\u306e\u307f\u30aa\u30fc\u30d7\u30f3\u306a\u3082\u306e \u6295\u7a3f\u3055\u308c\u305f\u7814\u7a76\u8ad6\u6587\u306e\u307f\u95b2\u89a7\u3067\u304d\u3001\u65b0\u3057\u3044\u51fa\u7248\u7269\u306e\u30ec\u30d3\u30e5\u30fc\u306a\u3069\u3001\u8ad6\u6587\u4ee5\u5916\u306e\u63b2\u8f09\u8a18\u4e8b\u3078\u306e\u30a2\u30af\u30bb\u30b9\u3092\u5236\u9650\u3059\u308b\u30bf\u30a4\u30d7\u3067\u3059\u3002\u81ea\u5206\u306e\u7814\u7a76\u306b\u95a2\u4fc2\u306e\u3042\u308b\u6700\u65b0\u306e\u7814\u7a76\u7d50\u679c\u3092\u63a2\u3059\u306e\u306b\u306f\u3001\u3053\u308c\u3067\u5341\u5206\u3067\u3057\u3087\u3046\u3002 3.\u6295\u7a3f\u3055\u308c\u305f\u7814\u7a76\u8ad6\u6587\u306e\u4e00\u90e8\u306e\u307f\u30aa\u30fc\u30d7\u30f3\u3067\u3001\u4ed6\u306e\u8ad6\u6587\u306b\u306f\u30a2\u30af\u30bb\u30b9\u3067\u304d\u306a\u3044\u3082\u306e 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